Oxycodone is a strong narcotic pain reliever and cough suppressant similar to an opioid analgesic class of drugs. The precise mechanism of action is not known, but it may involve the stimulation of opioid receptors in the brain.
Oxycodone does not eliminate the pain sensation but decreases discomfort by raising the tolerance to pain. Oxycodone is prescribed for the treatment of pain severe enough to require daily, around-the-clock, long-term treatment with a narcotic, and alternative treatment options are insufficient for the relief of moderate to severe pain.
Common Side effects of Oxycodone
- Lightheadedness
- Dizziness
- Sedation
- Nausea
- Vomiting
- Headache
- Rash
- Constipation
- Dry mouth
- Sweating
Mechanism of Action
Oxycodone and its active metabolites, noroxycodone, oxymorphone, and noroxymorphone have opioid agonist properties. These metabolites passively diffuse across the blood-brain barrier or may be actively transported by an unknown mechanism. Oxycodone and its active metabolites can selectively bind to the mu-type receptors, but also an agonist activity on kappa and delta opioid receptors in the central nervous system. Mu opioid receptors inhibit N-type voltage-operated calcium channels on activation. Long-term administration may cause less toxicity in comparison with morphine.
Drug interaction with oxycodone
Oxycodone, like other opioid pain-relievers, increases the effects of drugs that slow brain function, such as:
- Alcohol
- Barbiturates
- Skeletal muscle relaxants, for example, cyclobenzaprine, Benzodiazepines (lorazepam)
Combination of the above drugs and oxycodone may lead to increased respiratory depression.
Oxycodone should not be taken with any of the monoamine oxidase inhibitor (MAOI) class of antidepressants, for example, isocarboxazid, phenelzine, selegiline, and procarbazine or other drugs that inhibit monoamine oxidase, for example, linezolid. Such combinations of drugs may lead to confusion, high blood pressure, tremor, hyperactivity, coma, and death.
How Do I Take Oxycodone 30 mg?
It is important that you are using the Oxycodone 30 mg Tablet under the consultation of a pharmacist or your attending physician.
It is recommended that you should not suddenly stop taking the prescription Oxycodone pills if you have been using the drug for a length of time that is more than a short while. Because of this, the possibility of going through withdrawal and suffering with its symptoms will be lowered. The Oxycodone pills are released slowly over the course of the day (called extended release) and are available in a variety of doses.
Oxycodone Doses
It’s recommended to use the lowest dose possible for a short duration of time to relieve your pain.
Immediate-release forms: The typical starting dose is 5 mg to 15 mg by mouth every 4 to 6 hours as needed for pain.
Extended-release tablet: The typical starting dose is 10 mg by mouth every 12 hours.
Extended-release capsules: The typical starting dose is 9 mg by mouth every 12 hours with food.
Pain Relief Tablets
Oxycodone can be taken as a Pain Relief Tablet. It is prescribed to manage persistent, moderate to severe chronic pain. It can be taken with or without food. Patients should take this medicine regularly while you need it and not try to miss doses as this will make the medicine less effective. Buy painkiller medications at RxGeneric Pharma online to get medicines at your doorstep within 2-5 working days.